You can't own a gene

Human genome data should be public

Scientists announced earlier this week they have reason to believe a patent issued to Human Genome Sciences Inc. on a sequence of human DNA purported to be crucial in transmission of the AIDS virus may contain glaring errors. This announcement comes amid growing concern by scientists over openness of the Human Genome Project, which has seen significant advancements in sequencing and decoding of the nearly 3.5 billion chemicals in human DNA. Private companies, such as Human Genome Sciences, are often credited for the recent surge in discoveries, due in large part to their pioneering techniques designed to pull them ahead in the race to claim patents.

But, as more and more sequences based on human DNA effectively become the property of profiteering genetic research firms, scientists from around the world have begun to urge caution. As this endeavor marches ever closer to revolutionizing health care and disease treatment, we must urge openness of research, coupled with truly altruistic, long-term vision among all private interests laying claim to this veritable genetic gold mine.

The potential in decoding the human genome is not science fiction. Human Genome Sciences' patent claimed to have discovered a sequence intrinsic to blocking the spread of AIDS. With the right genetic information, new medicines may be developed to block AIDS and other diseases.

But, according to the L.A. Times, scientists have discovered potential errors with the patent on up to four grounds. A potential error this glaring in the patenting process should alert us to the very real threat of serious inaccuracy in other aspects of the genome process. If profiteering genetics companies rush modified genetic material to the market prematurely, the potential for serious error cannot be ignored.

With this patent potentially in dispute, other companies working on the genome project have begun to salivate at the potential of owning a sequence involved in AIDS. With billions in revenue at stake, this is a game where entire company stock valuations can be gauged by their ownership of certain strings of genetic material, whether or not the research is sound. Economics aside, the findings of the human genome project must be released to research universities and scientists without royalties on the patents. Companies must put research before short-term profits.

Last week, President Bill Clinton, along with Britain's Prime Minister, Tony Blair, released a declaration urging free access to human genome data. This declaration said, "To realize full promise of the research, raw fundamental data on the human genome, including the human DNA sequence and its variations, should be made freely available to scientists everywhere."

This statement comes as the University prepares to launch its new Life Sciences Institute, a potentially important resource for the decoding and testing of genetic discoveries. Unfettered access to human genome data is good for the University and necessary in the fight to ensure quality and safety in this exciting new scientific realm. Profit cannot get in the way of sound science. Human genome results must be shared for all people's benefit.


Originally on page 4 in the 3-24-2000 issue of the Daily.

 

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